Fig. 4
From: OC-STAMP is a potential biomarker and therapeutic target for Silicosis: an exploratory investigation
OC-STAMP induces Ferroptosis in MLE-12 cells and promotes fibrosis. A Establishment and intervention of OC-STAMP overexpression cell model. B, C Flow cytometry detection of overexpression of OC-STAMP and Fer-1 interfering with reactive oxygen species expression (n = 3). D, E Scratch assay to detect overexpression of OC-STAMP and Fer-1 interfering with MLE-12 cell migration (n = 3). F–K Immunoblotting to detect overexpression of OC-STAMP and Fer-1 intervening in the expression levels of OC-STAMP, Vimentin, α-SMA, GPX4, SLC7A11 proteins in MLE-12 cells (n = 3). All data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001