Fig. 1
From: OC-STAMP is a potential biomarker and therapeutic target for Silicosis: an exploratory investigation

SiO2 induce Silicosis. A Timeline of treatment with Silica particles (50 mg/ml) or 1 ml of sterile saline (Sham). Rats were executed on days 56, 112, and 168, respectively. B HE staining of lung tissues of rats in silica modelling group and Sham group at different periods (n = 5). B, C Masson staining and collagen content of lung tissue from rats in Silica moulding group and Sham at different periods (n = 5). B, D Immunohistochemical staining of Vimentin in lung tissues of rats in different periods in Sham group and Silicone model group (n = 5). All data were expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001