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Table 1 The comparison of clinical parameters between HAS patients and non-HAS patients

From: Gut commensal Parabacteroides distasonis exerts neuroprotective effects in acute ischemic stroke with hyperuricemia via regulating gut microbiota-gut-brain axis

 

Ischemic stroke patients

 

Variable

Non-hyperuricemia(n = 269)

Hyperuricemia

(n = 63)

P Value

Male (%)

165 (61.3)

38 (60.3)

0.881

Age (years)

66.55 ± 0.72

68.56 ± 1.72

0.240

BMI (kg/m2)

24.07 ± 0.26

24.00 ± 0.44

0.653

Previous stroke or TIA (%)

51 (18.90)

13 (20.60)

0.761

Hypertension (%)

196 (72.80)

51 (80.90)

0.185

Diabetes mellitus (%)

91 (33.80)

24 (38.00)

0.535

Hyperlipidemia (%)

122 (45.30)

33 (52.30)

0.314

Smoker (%)

89 (33.00)

21 (33.30)

0.970

Drinker (%)

80 (29.70)

19 (30.10)

0.948

Folic acid (ng/mL)

9.28 ± 0.26

9.91 ± 0.54

0.332

D-Dimer (mg/L)

0.36 (0.26, 0.64)

0.35 (0.24, 0.68)

0.755

HbA1c (%)

5.87 (5.48, 6.89)

5.73 (5.43, 6.88)

0.332

FPG (mmol/L)

5.20 (4.77, 6.66)

5.53 (4.98, 6.42)

0.365

UA (µmol/L)

293.15 ± 3.65

453.83 ± 7.79

< 0.001

Hcy (µmol/L)

10.90 (8.90, 13.40)

12.30 (10.70, 14.55)

0.003

TG (mmol/L)

1.45 (1.04, 1.90)

1.71 (1.30, 2.31)

0.003

Total cholesterol (mmol/L)

4.39 ± 0.07

4.45 ± 0.15

0.473

HDL (mmol/L)

1.01 (0.85, 1.24)

0.93 (0.78, 1.15)

0.195

LDL (mmol/L)

2.84 ± 0.06

2.79 ± 0.13

0.874

NIHSS score

2 (1, 4)

3 (1, 4)

0.099

mRS score

1 (0, 2)

2 (1, 3)

0.028

  1. Note: HbA1c, Glycosylated hemoglobin; FPG, Fasting Plasma Glucose; UA, Uric acid; Hcy: Homocysteine; TG, Triglycerides; HDL, High-Density Lipoprotein; LDL, Low-Density Lipoprotein; NIHSS, National Institutes of Health Stroke Scale; mRS, Modified Rankin Scale