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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer

Fig. 3

ScRNA-seq analysis revealing the effects of F1929-1458 on tumor immune microenvironment. A Unsupervised clustering of immune and non-immune cells in scRNA-seq data. B, C Manual cell annotation of immune and non-immune cells using selected cell type markers. D Bar plots showing the proportion changes of different types of immune cells between the F1929-1458 treated group and the control group. E Unsupervised clustering of T cells in scRNA-seq data. F, G Manual cell annotation of T cell subtypes using selected cell type markers. (H) Bar plots showing the proportion changes of T cell subtypes between the F1929-1458 treated group and the control group. (I) GO analysis of upregulated genes in T cells in the F1929-1458 treated group compared to the control group

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