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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Post-genome-wide association study dissects genetic vulnerability and risk gene expression of Sjögren’s disease for cardiovascular disease

Fig. 4

Manhattan plots. A Manhattan plot of MAGMA analysis based on MTAG results for IHD-SD (IHD as input data); B Manhattan plot of MAGMA analysis based on MTAG results for SD-IHD (SD as input data); C Manhattan plot of MAGMA analysis based on MTAG results for Stroke-SD (Stroke as input data); D Manhattan plot of MAGMA analysis based on MTAG results for SD-Stroke (SD as input data); E Manhattan plot of FUSION-TWAS analysis based on MTAG results for IHD-SD (IHD as input data); F Manhattan plot of FUSION-TWAS analysis based on MTAG results for SD-IHD (SD as input data); G Manhattan plot of FUSION-TWAS analysis based on MTAG results for Stroke-SD (Stroke as input data); H Manhattan plot of FUSION-TWAS analysis based on MTAG results for SD-Stroke (SD as input data). The red dashed line indicates the significance threshold for adjusted P values. MAGMA: Multi-marker Analysis of Genomic Annotation; MTAG: Multi-Trait Analysis of GWAS; IHD: ischemic heart disease; FUSION: Functional Summary-based Imputation; TWAS: Transcriptome-Wide Association Study

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Journal of Translational Medicine

ISSN: 1479-5876

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