Table 2 Characteristics of independent verification cohort (community-based)
Control | HFpEF | HFrEF | P-value (HFpEF vs control) | P-value (HFrEF vs control) | Overall | |
|---|---|---|---|---|---|---|
(n=18) | (n=22) | (n=12) | (n=52) | |||
Gender | ||||||
Female (%) | 12 (66.7%) | 15 (68.2%) | 5 (41.7%) | 0.9189 | 0.1758 | 32 (61.5%) |
Male (%) | 6 (33.3%) | 7 (31.8%) | 7 (58.3%) | 20 (38.5%) | ||
Age (years) | ||||||
Mean (SD) | 75.4 (8.61) | 81.5 (7.33) | 72.6 (13.2) | 0.0221 | 0.4775 | 77.3 (9.92) |
Median [IQR] | 75.5 [8.00] | 82.0 [8.50] | 73.0 [22.0] | 79.0 [11.5] | ||
Weight (kg) | ||||||
Mean (SD) | 83.0 (15.2) | 81.3 (19.9) | 84.5 (22.1) | 0.7746 | 0.8232 | 82.6 (18.6) |
Median [IQR] | 82.9 [23.1] | 83.3 [32.5] | 81.0 [41.6] | 82.6 [30.2] | ||
HR (BPM) | ||||||
Mean (SD) | 70.9 (16.8) | 75.4 (16.2) | 75.2 (9.45) | 0.2947 | 0.211 | 73.8 (15.0) |
Median [IQR] | 65.5 [20.8] | 74.0 [19.3] | 77.5 [12.0] | 72.0 [18.5] | ||
SBP (mmHg) | ||||||
Mean (SD) | 147 (21.0) | 153 (19.6) | 144 (26.1) | 0.4198 | 0.4208 | 149 (21.5) |
Median [IQR] | 144 [29.8] | 154 [25.8] | 142 [27.3] | 150 [27.3] | ||
DBP (mmHg) | ||||||
Mean (SD) | 71.1 (14.8) | 73.9 (15.1) | 73.7 (15.7) | 0.5578 | 0.6476 | 72.8 (14.9) |
Median [IQR] | 72.5 [15.8] | 72.0 [21.0] | 72.5 [17.8] | 72.0 [19.3] | ||
EF (%) | ||||||
Mean (SD) | 65.4 (5.82) | 63.8 (6.40) | 37.4 (10.5) | 0.4362 | <0.0001 | 57.7 (13.9) |
Median [IQR] | 67.0 [8.00] | 64.5 [6.25] | 39.5 [16.3] | 62.0 [15.8] | ||
Missing (%) | 2 (11.1%) | 2 (9.1%) | 0 (0%) | 4 (7.7%) | ||
BNP (pg/ml) | ||||||
Mean (SD) | 55.1 (71.1) | 224 (114) | 223 (155) | <0.0001 | 0.0007 | 165 (137) |
Median [IQR] | 25.5 [42.7] | 201 [161] | 231 [274] | 135 [205] | ||
Na (mEq/l) | ||||||
Mean (SD) | 140 (2.85) | 139 (4.09) | 139 (2.73) | 0.7503 | 0.6781 | 139 (3.37) |
Median [IQR] | 140 [2.00] | 140 [5.75] | 140 [1.25] | 140 [3.50] | ||
K (mEq/l) | ||||||
Mean (SD) | 4.29 (0.310) | 4.15 (0.434) | 4.33 (0.452) | 0.258 | 0.8271 | 4.24 (0.399) |
Median [IQR] | 4.35 [0.450] | 4.15 [0.525] | 4.20 [0.375] | 4.25 [0.425] | ||
CL (mEq/l) | ||||||
Mean (SD) | 105 (2.62) | 102 (5.62) | 104 (4.37) | 0.0369 | 0.3447 | 104 (4.62) |
Median [IQR] | 106 [2.50] | 103 [6.75] | 105 [4.25] | 105 [5.25] | ||
Urea (mmol/l) | ||||||
Mean (SD) | 7.26 (2.73) | 8.32 (3.64) | 9.14 (2.41) | 0.3147 | 0.0375 | 8.14 (3.12) |
Median [IQR] | 6.65 [2.30] | 7.40 [3.08] | 9.40 [3.33]cl | 7.40 [3.85] |