Fig. 2

Entropy, stemness, and TMM vary according to the cell type at the single-cell level. a Box plot of the telomerase TERT pathway activity in high-grade entropy clusters (left) and box plot of the ALT instability pathway activity in high-grade clusters (right). b Box plot of the telomere maintenance mechanism pathway activity in high-grade clusters. c Boxplot of the telomere maintenance mechanism pathway activity in benign/low-grade clusters. d Gene Ontology network in enriched genes of high-grade clusters. e Gene Ontology network in enriched genes of benign/low-grade clusters. f Protein–protein interaction (PPI) of the enriched genes in high-grade clusters. g PPIs of the enriched genes in the benign/low-grade clusters. h Metabolic pathway activity in high-grade entropy clusters. ALT: Alternative Lengthening of Telomeres; TERT: Telomerase Reverse Transcriptase; TMM: Telomere Maintenance Mechanism