Fig. 1

Isolation and identification of exos. a, Isolation and purification of EVs from the conditioned media by ultracentrifugation. b, Size distribution of EVs analyzed by NTA. c, The ζ-potential of EVs. d, The morphology of EVs characterized by TEM, Scale bar = 100 nm. e, Proteins expression of exosomal positive and negative biomarkers detected by western blot analysis