Fig. 1

, Selinexor and JQ1 synergistically kill AML cells. Cell viability assays under the influence of different concentrations of Selinexor and JQ1, respectively in cells Kasumi-1 (A), MOLM13 (E), MV4-11 (I) and THP1 (M). Inhibition rate heat map at different concentrations of Selinexor and JQ1, respectively in cells Kasumi-1 (B), MOLM13 (F), MV4-11 (J) and THP1 (N). Drug synergy index at different concentrations of Selinexor and JQ1 in different AML cells, respectively in cells Kasumi-1 (C), MOLM13 (G), MV4-11 (K) and THP1 (O). The Highest Single Agent (HSA) scores for these two drugs in Kasumi-1 (D), MOLM13 (H), MV4-11 (L) and THP1 (P). All experiments were performed with at least three independent replicates