Fig. 5

Assessment of the predictive performance of PFASRHSig. A Risk score distribution in the TCGA-LIHC cohort. The cutpoint is set at − 1.66953, the median risk score. The heatmap presents the varied expression levels of model genes across high and low PFASRHSig group. (B-G) Time-dependent ROC curves assessing 1-, 3-, and 5-year survival prediction across six cohorts: CHCC (n = 159)-AUC: 0.824, 0.803, 0.779; LICA (n = 152)-AUC: 0.802, 0.767, 0.747; LIRI (n = 202)-AUC: 0.755, 0.812, 0.834; TCGA-LIHC (n = 355)-AUC: 0.728, 0.708, 0.732; GSE14520 (n = 221)-AUC: 0.721, 0.717, 0.725; GSE54236 (n = 78)-AUC: 0.916, 0.907, 0.902