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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway

Fig. 4

Knockdown of eIF3a ameliorated pulmonary hypertension induced by MCT. A Image captured by fluorescence microscopy to trace the location and expression of injected AAV in rodent lung tissues. B, C Western blot and the statistical result of eIF3a proteins. D Representative image of RVSP measurement. E Summarized data of RVSP. F Summarized data of right ventricle/left ventricle plus septum. G Summarized data of right ventricle/body weight. H Representative image of H&E staining (Scale bar: 50 μm). I Summarized data of WT%. Data are represented as the mean ± SD, n = 6–10, ***P < 0.001 vs. Control group, ###P < 0.001 vs. MCT group

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Journal of Translational Medicine

ISSN: 1479-5876

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