Fig. 3
From: Revealing multiple biological subtypes of schizophrenia through a data-driven approach
Differences between the three gut subtypes and their corresponding biomarkers. (a) Comparison of alpha diversity between GSs. ***pBonferroni< 0.001. (b) Differences in RA between GSs. (c) Abnormal relationships between genera in GSs compared with HCs. (d) Differences in clinical symptoms and cognitive performance vary among GSs and HCs, which are shown as normalized values, where P, N, G, and T represent PANSS PScore, NScore, GScore, and TScore, respectively. M1-M5 and M represent processing speed, attention/vigilance, working memory, verbal learning, visual learning, and total scores of the first five dimensions of the MCCB, respectively. ■pall< 0.05, ◆pGSs< 0.05, □pGS1 vs. GS2< 0.05, and □pGS2 vs. GS3< 0.05 (with Bonferroni correction); all values are displayed in Supplemental Table S6. (e) Biomarkers of the MCCB score in GS1. (f) Biomarkers of the PANSS and MCCB scores in GS2 after bootstrapping. (g) Biomarkers of the PANSS and MCCB scores in GS3 after bootstrapping. For the sake of the aesthetics of the graph, the scatter plot was plotted by selecting only the 150 data points obtained after bootstrapping. The error bands in figures (f-g) represent 95% confidence interval