Fig. 2
KLF5 is related to PARPi resistance and poor prognosis of ovarian cancer. A Enrichr analysis of genes highly expressed in A2780-olaR cells compared to A2780 cells based on GSE153867 data set. B Western blot image of KLF5 protein expression in A2780, A2780-olaR, SKOV3 and SKOV3-olaR cells. C KLF5 protein expression in different ovarian cancer cells. D Correlation analysis between KLF5 protein expression and olaparib IC50 in different ovarian cancer cells. E KLF5 protein expression detected by western blot in ovarian cancer and fallopian tube tissues. N1-N5 represent normal fallopian tube tissues obtained from patients who underwent hysterectomy and salpingectomy for benign uterine diseases. T1-T8 represent ovarian cancer tumor tissues. F Representative immunohistochemistry images of KLF5 expression in ovarian cancer tissue microarrays from Qilu Hospital. G Overall survival analysis of ovarian cancer tissue microarrays from Qilu Hospital, grouped according to KLF5 expression. H Progression-free survival analysis of ovarian cancer tissue microarrays from Qilu Hospital, grouped according to KLF5 expression. P value was obtained by Log-rank test