Table 1 Clinical Characteristics of Discovery and Validation Cohorts

No. of samples

43

25

Age, mean ± sd

68 ± 8

66 ± 8

Sex, n (%)

 Female

25 (58.1)

9 (36)

 Male

18 (41.9)

16 (64)

Smoking Status, n (%)

 Former

9 (20.9)

6 (24)

 Current

33 (76.7)

17 (68)

 Never

1 (2.3)

2 (8)

ECOG status, n (%)

 1

21 (65.6)

21 (80.8)

 2

8 (25)

2 (7.7)

 3

3 (9.4)

3 (11.5)

PD-L1 expression, n (%)

 > 50%

19 (44.2)

11 (44)

 < 50%

24 (55.8)

14 (56)

PFS, n (%)

 > 12 months

17 (39.5)

11 (44)

 < 12 months

26 (60.5)

14 (56)