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Table 2 Clinical characteristics of children for Western blotting validation

From: High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension

Groups

Con

HP

HHYP

P value

Cases, n

8

8

8

—

Male, n

8

8

8

>0.999*; >0.999#; >0.999&

Age (± s, years)

10.12 ± 0.96

10.75 ± 1.71

13.37 ± 0.65

0.699*; 0.055#; 0.115&

sSBP (± s, mmHg)

102.50 ± 3.20

129.75 ± 3.49

139.50 ± 5.18

<0.001*; <0.001#; 0.104&

sDBP (± s, mmHg)

66.00 ± 2.91

76.00 ± 4.33

80.00 ± 4.78

0.098*; 0.024#; 0.496&

BMI (± s, kg/m2)

17.33 ± 0.67

21.16 ± 0.89

21.78 ± 0.54

0.001*; <0.001#; 0.552&

Cholesterol (mmol/L)

3.70 ± 0.19

3.54 ± 0.18

4.18 ± 0.22

0.571*; 0.109#; 0.065&

TG (mmol/L)

0.85 ± 0.10

1.19 ± 0.24

1.32 ± 0.21

0.235*; 0.105#; 0.642&

HDL (mmol/L)

1.49 ± 0.12

1.11 ± 0.68

1.06 ± 0.77

0.008*; 0.003#; 0.707&

LDL (mmol/L)

2.07 ± 0.17

2.12 ± 0.17

2.82 ± 0.23

0.845*; 0.011#; 0.017&

Hcy (µM)

4.94 ± 1.25

7.25 ± 0.36

23.58 ± 4.32

0.537*; <0.001#; <0.001&

  1. sSBP: mean supine systolic blood pressure
  2. sDBP: mean supine diastolic blood pressure
  3. BMI: body mass index
  4. TG: triglyceride
  5. HDL: High density lipoprotein
  6. LDL: Low-density lipoprotein
  7. *: HP vs. Con; #: HHYP vs. Con; &: HHYP vs. HP