Fig. 1

The relationship between gene set size and prognostic model performance across three cancer types. To examine the relationship between gene set size and prognostic model performance, correlation analysis was performed, with all analyses repeated 100 times. For colorectal cancer: panel (A) shows the relationship between AUC and gene set size, (B) shows the relationship between gene set size and log-rank p-value, and (C) shows the relationship between gene set size and hazard ratio (HR). Similarly, panels (D), (E), and (F) show the corresponding relationships for lung cancer, and panels (G), (H), and (I) show the corresponding relationships for liver cancer