Fig 2
Identification of lesion cells and trajectory of tissue development. A Copy number variations analysis results. The left panel shows the CNV analysis results of the diseased lymph node tissue (hyaline vascular type as an example), and the right panel shows the CNV analysis results of the normal lymph node tissue. B Differences in the number of cells in normal versus diseased lymph node tissue in advanced stages of development. The first row is the number of plasma cells, myofibroblasts, LECs and cycling cells in advanced stages of development in normal lymph node tissue. The following row shows the number of plasma cells, myofibroblasts, LECs and cycling cells in advanced stages of development in diseased lymph node tissue (hyaline vascular type as an example).C Genes highly expressed at nodes during tissue development. The figure on the left shows the genes that are predominantly highly expressed at the nodes in normal lymph node tissue. The middle and right panels show genes that are highly expressed at nodes during the development of lesion tissue.