Fig. 5
From: E2F8-induced GRPEL2 promoted colorectal cancer progression via targeting TIGAR
GRPLE2 expression level was positively correlated with TIGAR in CRC. A Expression profile of TIGAR in clinical samples generated from TCGA database. B Relative expression of TIGAR in 68 paired normal and tumor tissues of CRC patients. C Correlation of GRPEL2 and TIGAR expression levels in CRC tumors. A–C, N = 68. D Tissue staining results of TIGAR in normal and tumor tissues from CRC patients. E Kaplan Meier analysis of 68 CRC patients divided based on TIGAR expression. F mRNA of TIGAR in CRC cells after inhibition of GRPEL2 and G protein levels of TIGAR in CRC cells after inhibition or overexpression of GRPEL2. F–G, N = 3, *P < 0.05, **P < 0.01, ***P < 0.001