Fig. 2
From: E2F8-induced GRPEL2 promoted colorectal cancer progression via targeting TIGAR
Inhibition of GRPEL2 suppressed proliferation and migration of CRC. A mRNA and B protein levels of GRPEL2 in DLD-1 and HCT116 cells after indicated treatments. (C) EdU staining of cell proliferation after indicated treatments. D Transwell results of DLD-1 and HCT116 cells after indicated treatments. A–D, N = 3. E Tumor growth curve, F tumor weight and G tumor images of DLD-1 and HCT116 xenograft models after indicated treatments. H Images and statistical results of Ki-67 staining in xenograft tumor tissues. I Live imaging and J liver tissue H&E staining showing CRC cell metastasis. E–J, N = 6, *P < 0.05, **P < 0.01, ***P < 0.001