Fig. 1

TRIM44 is upregulated in the retina of diabetic rats. (A) A schematic illustration of the experiments was presented. (B) The blood glucose (left) and body weight (right) of rats were measured at indicated time points. (C-D) After 12 weeks of induction, the mRNA and protein expression levels of TRIM44 in the rat retinal tissues were measured. (E) Representative images of immunofluorescence staining for TRIM44 (red) in the rat retina (magnification × 200). DR, diabetic retinopathy; STZ, streptozotocin; GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer. ***P < 0.001. n = 6 per group