Fig. 2
Differentiation and metabolic profiles of CARCIK cells. (A) Immunophenotype along with CAR expression of CARCIK-CD19 cells produced following Protocol 2. (B) Memory phenotype comparison between Protocol 1- and Protocol 2- derived CARCIK-CD19 cells. (C–E) Intradonor memory and metabolic differences (analyzed by Seahorse T Cell Metabolic Kit) between Flask- and G-Rex-derived CARCIK-CD19 cells generated following Protocol 2. OCR: Oxygen Consumption Rate ECAR: Extracellular Acidification Rate