Fig. 5

Adoptive transfer of CD8⁺T cells in CVB3-induced viral myocarditis. (A-B) Schematic workflow of CD8⁺T cell transfer. (C)Weight changes of mice in different groups during the experimental process. (D) Representative echocardiographic image of different groups. (E)The ejection fraction (Left) and fraction shortening (Right) change of three groups. (F) Representative HE staining images in different groups. Scale bar, 20 μm. (G) The plasma expression level of cardiac troponin T(cTnT) (Left) and TNF-α (Right) in different group. (H)Tunel staining revealed the cell apoptosis in the myocardium of mice in different groups. Broken DNA was labeled with CF488 (green). Nuclei were stained with DAPI (blue). Scale bar, 50 μm. Unpaired t-test was used for analysis. Data are presented as mean ± SD (n = 5 biologically independent samples). *p < 0.05; **p < 0.01; ***p < 0.001