Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis

Table 3 The association of NOAF treatment medications with outcomes in the prematch cohort

Outcome	Rate Control (n = 459)	Rhythm Control (n = 127)	Univariable analysis HR/OR (95%CI)	P-value	Multivariable analysis HR/OR (95%CI)	P-value
28-day mortality n(%)	178 (38.8)	63 (49.6)	HR 1.51 (1.14, 2.02)	0.004	HR 0.96 (0.70, 1.32)	0.799
ICU mortality n(%)	111 (24.2)	58(45.7)	OR 2.64 (1.75, 3.97)	< 0.001	OR 1.12 (0.67, 1.88)	0.664
1-year mortality n(%)	254 (55.3)	82 (64.5)	HR 1.40 (1.09, 1.79)	0.008	HR 0.96 (0.73, 1.26)	0.747

Multivariable analysis adjusted for age, gender, Sequential Organ Failure Assessment score, heart failure, hypertension, renal failure, respiratory failure, coronary artery disease, need for renal replacement therapy, need for mechanical ventilation, need for vasopressors, blood urea nitrogen (BUN), creatinine, sodium, chloride, calcium, glucose, potassium, magnesium levels inflammatory markers (white blood cell, neutrophil percentage)
HR hazard ratio, OR Odds Ratio, CI confidential interval

ISSN: 1479-5876