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Table 2 Contingency analysis for gene expression association (Fisher exact test)

From: Gene expression analysis in circulating tumour cells to determine resistance to CDK4/6 inhibitors plus endocrine therapy in HR + /HER2- metastatic breast cancer patients

Gene 1

Gene 2

Visit

Association type

p-value

SNAIL1

VIM

V1

Positive

0.008

PI3KCG

JAK2

V1

Positive

0.000

PI3KCG

CUL1

V1

Positive

0.004

STAT3

PRKCB

V1

Positive

0.008

ALDH1A1

PLS3

V1

Positive

0.020

CDK4

CDK6

V1

Positive

0.008

CDK4

CDKN1C

V2

Negative

0.030

STAT3

MAPK3

V2

Positive

0.003

STAT3

PRKCB

V3

Positive

0.049

STAT3

JAK2

V3

Positive

0.005

STAT3

ALDH1A1

V3

Positive

0.005

BAX

CASP8

V3

Positive

0.003

CDK4

CDK6

V3

Positive

0.060

SNAIL1

VIM

V3

Positive

0.000