Table 1 Summary of six critical genes identified in the study
Symbol | P_TWAS_Discovery | P_TWAS_Duplication | P_MR_Discovery | OR_MR_Discovery | P_MR_Duplication | OR_MR_Duplication | P_SMR_Discovery | OR_SMR_Discovery | P_SMR_Duplication | OR_SMR_Duplication |
|---|---|---|---|---|---|---|---|---|---|---|
BRCA1 | 2.44E−04 | 1.58E−02 | 1.28E−02 | 1.25E + 00 | 4.04E−02 | 1.26E + 00 | 1.31E−02 | 1.25E + 00 | 4.09E−02 | 1.26E + 00 |
EZH1 | 5.87E−04 | 4.44E−02 | 2.48E−02 | 2.10E + 00 | 2.90E−02 | 2.87E + 00 | 3.15E−02 | 2.10E + 00 | 3.60E−02 | 2.87E + 00 |
FAM13A | 2.10E−03 | 1.40E−02 | 1.39E−04 | 1.31E + 00 | 3.97E−02 | 1.36E + 00 | 1.03E−04 | 1.30E + 00 | 2.37E−03 | 1.33E + 00 |
SFR1 | 2.68E−03 | 4.50E−07 | 2.01E−02 | 7.20E−01 | 4.59E−04 | 4.44E−01 | 2.19E−02 | 7.20E−01 | 6.92E−04 | 4.44E−01 |
ANO9 | 3.73E−02 | 2.60E−07 | 4.93E−02 | 1.13E + 00 | 2.91E−03 | 1.31E + 00 | 4.98E−02 | 1.13E + 00 | 3.05E−03 | 1.31E + 00 |
CCDC200 | 2.43E−04 | 1.87E−02 | 5.35E−04 | 4.82E−01 | 1.88E−02 | 4.70E−01 | 1.17E−03 | 4.82E−01 | 2.27E−02 | 4.70E−01 |