Fig. 6

A UMAP plot showing the clustering of cells into 18 distinct clusters based on single-cell RNA sequencing analysis. Each cluster is color-coded and labeled accordingly. B UMAP plot comparing cell types between control (ctrl) and IPF samples. Different cell types are indicated by color, showing the distribution of cells across conditions. C Heatmap displaying the gene expression levels of essential genes (ANO9, BRCA1, CCDC200, EZH1, FAM13A, SFR1) across various cell types. The color intensity represents the expression values, with red indicating upregulation and blue indicating downregulation. Asterisks indicate statistically significant differences in expression (**p < 0.01, *p < 0.05)