Fig. 5

A Volcano plot showing the differential expression of critical genes. The x-axis represents the logFC, and the y-axis represents the -log10(P-value). Genes are color-coded based on their expression changes: blue for downregulated genes, red for upregulated genes, and grey for unchanged genes. Notable upregulated genes include FAM13A, while SFR1 and EZH1 are among the downregulated genes. B Dot plot summarizing the functional enrichment analysis of critical genes across different categories, including Biological Process (BP), Cellular Component (CC), Molecular Function (MF), and Kyoto Encyclopedia of Genes and GenomesKEGG pathways. The dot color represents the −log10(P-value), and the size of the dots indicates the gene ratio. Significant pathways associated with BRCA1, BRCA1/SFR1, and EZH1 are highlighted