Fig. 8

TMEM176B inhibits EMT via the Wnt/β-catenin signaling pathway. A2780 cells were transfected with negative control or TMEM176B overexpresion lentiviruses, and then incubated with LiCl (10 mmol/L) or vehicle (DMSO) for another 24 h. (A-B) Western blotting determined the reversal efficiency of LiCl on E-cadherin, MMP9, and SNAI2 in both the LVNC and LVTMEM176B groups. *P < 0.05; **P < 0.01, n = 3