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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Apoptotic cell-derived extracellular vesicles-MTA1 confer radioresistance in cervical cancer by inducing cellular dormancy

Fig. 6

apoEV-MTA1 promotes redioresistance of CC in vivo. (A) Tumor growth curves of the CC xenograft model in vivo. *P < 0.05. (B) Kaplan-Meier survival analysis of mice injected with SiHa cells treated with either shMTA1-apoEVs or shNC-apoEVs (n = 3 per group, P < 0.05, log-rank test). (C) Western blot results indicating the levels of MTA1 and NR2F1 expression in tumor tissue from each group of mice. (D) Representative IHC images showing the expression levels of MTA1 and NR2F1 in tumor sections from each group, with images captured at 200× magnification and a scale bar of 50 μm

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