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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Integrating single-cell and bulk RNA sequencing data to characterize the heterogeneity of glycan-lipid metabolism polarization in hepatocellular carcinoma

Fig. 3

Clinical parameters and genomic alterations correlates of metabolic subtypes. a–c Kaplan–Meier survival analyses demonstrating poorer overall survival in glycan-HCC versus lipid-HCC in TCGA (a), ICGC (b), and CPTAC (c) cohorts. Survival plots were generated by using R package “survminer”. d Heatmap showing associations between metabolic subtypes, clinical parameters, and mutational profiles. e Genomic instability metrics (aneuploidy/CNA/HRD scores) were elevated in glycan-HCC, and tumor mutation burden showed no significant difference

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Journal of Translational Medicine

ISSN: 1479-5876

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