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Fig. 10 | Journal of Translational Medicine

Fig. 10

From: Integrating single-cell and bulk RNA sequencing data to characterize the heterogeneity of glycan-lipid metabolism polarization in hepatocellular carcinoma

Fig. 10

Identification of major signaling changes in different subtypes. Bubble plots illustrate the increased (a) and decreased (b) signaling pathways in glycan-HCC, depicting the probabilities of ligand-receptor interactions. c The gene expression of SPP1 was significantly up-regulated in macrophages associated with glycan-HCCs. d The SPP1-CD44 ligand-receptor interactions (T cells —> TAMs) were markedly up-regulated in glycan-HCCs compared to those in lipid-HCCs

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Journal of Translational Medicine

ISSN: 1479-5876

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