Fig. 1

Screening potential targets for platinum-based chemotherapy resistance in gastric cancer based on public databases. A The flowchart of the screening process of BAIAP2L2. B Differential expression analysis between normal and tumor tissues which were extracted from the TCGA database. C Differential expression analysis between relapse group and non-relapse group which was grouped by whether relapse after receiving cisplatin-based chemotherapy. D Survival analysis, including univariate Cox analysis and K-M method, indicated that BAIAP2L2 was relatively prominent among the cisplatin recurrence related genes highly expressed in tumors correlated with prognosis. E Candidate genes were the intersection of differential expression analysis between normal and tumor, relapse and non-relapse, and survival analysis. F The treemap via GO analysis for possible mechanism of cisplatin recurrence in gastric cancer mining with the 25 cisplatin recurrence related genes highly expressed in tumors