Fig. 4
From: Understanding pre-metastatic niche formation: implications for colorectal cancer liver metastasis
Prevention and treatment strategies against CRCLM based on PMN. A radiomic approach combined with clinical characteristics is intended to diagnosis metastatic niches early. Organoids derived from mice and patient samples provide improved models and evaluation systems for PMN mechanisms research and drug development in CRCs. Traditional Chinese medicine compound preparations and plant-derived natural ingredients show promise in regulating PMN and potentially preventing CRCLM