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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Biomarker identification for Alzheimer’s disease through integration of comprehensive Mendelian randomization and proteomics data

Fig. 1

Overview of the study design. EA, European ancestry; UKB-PPP, UK biobank Pharma Proteomics Project; MR, Mendelian randomization; cis-pQTLs, cis protein quantitative trait loci within ± 1 Mb from TSS of the protein-coding gene; GWAS, genome-wide association study; Mb, megabase; TSS, translation start site; FDR, false discovery rate; PP.H4, posterior possibility of hypothesis 4; SNP, single nucleotide polymorphisms; cis-eQTLs, cis gene expression quantitative trait loci within ± 1 Mb from TSS of protein-coding gene; mRNA, messenger RNA; AA, African ancestry

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Journal of Translational Medicine

ISSN: 1479-5876

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