Fig. 2
From: Gut microbiota: a hidden player in polycystic ovary syndrome
Illustrates the effects of gut dysbiosis in the development of PCOS. Gut dysbiosis leads to increased gut permeability, causing the translocation of microbial compounds to enter systemic circulation. It leads to chronic systemic inflammation that contributes to insulin resistance, hyperandrogenism, and mood disorder, all characteristics of PCOS. These metabolic and hormonal disorders emerge clinically as irregular menstrual periods and hirsutism