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Table 1 Characteristics of the donors of liver tissue from the cohort data used in the study

From: Indole-3-propionic acid promotes hepatic stellate cells inactivation

 

Clinical characteristics

Total, N (male/female)

116 (27/89)

Age (years)

46.8 ± 9.3

BMI (kg/m2)

42.7 ± 5.0

fS-Total cholesterol (mmol/l), N = 110

4.3 ± 0.8

fS-HDL cholesterol (mmol/l), N = 110

1.1 ± 0.3

fS-LDL cholesterol (mmol/l), N = 109

2.5 ± 0.7

fS-Triglycerides (mmol/l), N = 109

1.3 (0.9–2.0)

fP-glucose (mmol/l)

5.8 ± 0.7

fS-insulin (mU/l), N = 115

14.7 (10.1–20.1)

Steatosis grade, N

< 5%

62

 5–33%

41

 33–66%

6

> 66%

7

 Lobular inflammation, N

19

 Ballooning, N

18

 Fibrosis stage, N

38

  1. One-way ANOVA continuous variable or χ2 test. Data are present as mean ± SD. N- number of individuals, BMI- Body mass index, fS- fasting serum, fP- fasting plasma, HDL- high-density lipoprotein, LDL- low-density lipoprotein, SS-simple steatosis, NASH- non-alcoholic steatohepatitis