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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Neuronal guanine nucleotide exchange factor promotes the axonal growth and cancer cell proliferation via Ephrin-A3/EphA2 axis in lung adenocarcinoma

Fig. 5

Ephrin-A3/EphA2 axis facilitated NGEF to promote axonal growth. (A) PPI analysis. (B) mRNA level of different EphA subtypes. One-way ANOVA. ***P < 0.001. (C) mRNA level of different Ephrin-A subtypes. One-way ANOVA. ***P < 0.001. (D) Western blot of Ephrin-A3 and EhA2. (E) Co-IP of NGEF and EphA2. (F) Co-IP of Ephrin-A3 and EphA2. (G) mRNA level of EphrinA3. One-way ANOVA. **P < 0.01, ***P < 0.001. (H) Protein level of EphrinA3. One-way ANOVA. *P < 0.05, **P < 0.01, ***P < 0.001. (I) β-tubulin III staining of neurons. Scale bar: 20 μm. (J) Dendritic length between groups. One-way ANOVA. ** P < 0.01, ***P < 0.001

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Journal of Translational Medicine

ISSN: 1479-5876

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