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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Integrative multi-omics analysis of radionuclide-induced intestinal injury reveals the radioprotective role of L-citrulline through histone H3-mediated Cxcl3

Fig. 7

Schematic representation of the discovery mechanism of the radioprotective ability of L-citrulline. L-citrulline increases the citrullination of histone H3 (R17), which regulates the expression of Cxcl3. Cxcl3 has a radio-protective effect in intestinal cells. L-citrulline plays its role in radioprotection via H3Cit17-Cxcl3 axis

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Journal of Translational Medicine

ISSN: 1479-5876

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