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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Spatial interaction mapping of PD-1/PD-L1 in head and neck cancer reveals the role of macrophage-tumour barriers associated with immunotherapy response

Fig. 6

Spatial contexts as sites of functional interactions between CNs colocalization. (A) Barycentric coordinate projection of windows of cells assigned to Tumour, isPLA−, Tumour & immune, PLA+/−, and Tumour and immune, isPLA+. Outlined regions along the edges and vertices highlight abundant CN and interfaces specifically for CR patients, and C) shows these regions for the PD group. (B) SCM of combinations comprising more than 0.001% of total cells. Black rectangles indicate SCs with the highest frequency of Tumour, isPLA−, Tumour & immune, isPLA+/−, and Tumour and immune, isPLA+ neighbourhoods for CR patients, and D) shows these neighbourhoods for the PD group

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Journal of Translational Medicine

ISSN: 1479-5876

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