Fig. 5
Enhanced PD-L1 and IL6 expression in TMPRSS2high cells. A: mRNA expression by qPCR analysis was performed to assess the expression levels of PD-L1 in both TMPRSS2high cells and mock-transfected control cells. B: Flow cytometry was used to evaluate PD-L1 surface expression in TMPRSS2 transfectants of MCF-7 and EA.Hy926 cells (n = 3). The results are presented as MFI. C: A correlation plot depicts the relationship between TMPRSS2 and PD-L1 expression in blood samples from COVID-19 patients (COVID-19db). D: The supernatants from TMPRSS2high and TMPRSS2low EA.Hy926 cells were assessed for IL-6 secretion using ELISA. The data represents the mean from three independent experiments