Fig. 1

Increased levels of TMPRSS2 expression in blood samples from COVID-19 patients and in cell lines infected with SARS-CoV-2 compared to uninfected controls. A: TMPRSS2 expression levels were analyzed in blood samples from 24 healthy individuals and 62 patients with COVID-19. These data were obtained from whole blood transcriptomics analyses (COVID19db). B: TMPRSS2 expression in Calu3 lung carcinoma epithelial cells was evaluated after infection with SARS-CoV-2 (GEO: GSE147507). C: The TMPRSS2 transcriptomic expression across various tumor types (red bars) and their adjacent normal tissues (blue bars) was examined using TCGA datasets. The results are displayed in a bar chart. t.test, ns: p > 0.05; *: p ≤ 0.05; **: p ≤ 0.01; ***: p ≤ 0.001