Fig. 9

YSV induced cell cycle arrest and apoptosis of OSCC by regulating PI3K/AKT signaling pathway in vivo. The protein expression levels of CDK1, Cyclin B1, Bcl2, Bax, Cleaved caspase-3, PTEN, PI3K, p-PI3K, AKT and p-AKT in the tumor tissues of the mice injection of SCC-15 cells (left) and CAL-27 cells (right)