Fig. 5

RNA-seq and molecular docking analysis revealed that PTEN/PI3K/AKT was the core signaling pathway of YSV against HNSCC. (a) KEGG pathway analysis; (b) A visualized PI3K/AKT pathway heatmap with related gene expression levels; (c) Molecular docking between YSV and PTEN, PI3K and AKT; (d) Binding affinities of YSV with the proteins in (c)