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Fig. 10 | Journal of Translational Medicine

Fig. 10

From: Targeted inhibition of the PTEN/PI3K/AKT pathway by YSV induces cell cycle arrest and apoptosis in oral squamous cell carcinoma

Fig. 10

The combination usage of YSV and LY294002 inhibited OSCC progression in vivo. (a) Representative images of tumor samples; (b) Tumor volume (left) and tumor weight (right) of the mice injection of SCC-15 cells treated with PBS, YSV, LY294002, or the combination of YSV and LY294002; (c) HE staining images of tumor, heart, liver, spleen, lung and kidney of the mice treated with PBS, YSV, LY294002, or the combination of YSV and LY294002. * P < 0.05, ** P < 0.01, *** P < 0.001, n = 3. Asterisks represent the differences between mice treated with YSV or LY294002 and PBS; pounds represent the differences between mice treated with the combination of YSV and LY294002 and LY294002; ampersands represent the differences between mice treated with combination of YSV and LY294002 and YSV

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