Fig.4

The effective protection of antibody cocktails in golden Syrian hamsters challenged with SARS-CoV-2 XBB.1.16. (a) Groups of hamsters that infected SARS-CoV-2 were divided into four groups (n = 6 per group). All animals were challenged with SARS-CoV-2 XBB.1.16 intranasally and 20 mg/kg antibodies were administrated i.p (group A) or i.n (group B) four hours prior-infection, and i.p (group C) 20 hours post-infection. Equal volume of anti-HIV antibody was used as a control (group D). (b) Viral load of nasal swabs were monitored daily. (c) Viral load in lung, trachea, turbinalia and intestine tissues were examined at day 7. (d) Representative histopathology of lungs in hamsters of four groups. The images are shown as 100 ×