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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus

Fig. 1

scRNA-seq illustrates a high-resolution immune and structural landscape of the intestinal epithelial layer in lupus mice. (A) Workflow of the experimental pipeline. (B) UMAP plot depicting main cell types identified in intestinal epithelial layer, based on a total of 38,737 cells. (C) Feature plots representing expression of Cd45, Trac, Trdc, Cd8a, Cd8b1, and Cd79a. (D) Dot plot illustrating the selected top DEGs for immune cells and structural cells in the intestinal epithelial layer. Color saturation denotes the strength of gene expression on average, while the size of dots corresponds to the proportion of each cell cluster expressing the gene. DC: Dendritic cells

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Journal of Translational Medicine

ISSN: 1479-5876

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