Fig. 5
From: Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis
Tissue-specific eQTL and pQTL analysis for psoriasis-associated genes and proteins. A Venn diagram showing the overlap of eQTLs across different tissue types: sun-exposed skin (10 unique eQTLs, dark blue), sun-unexposed skin (5 unique eQTLs, green, with 20 overlapping with sun-exposed skin), whole blood eQTL in replication cohort (12 unique eQTLs, light blue), whole blood eQTL in discovery cohort (35 unique eQTLs, pink), and eQTLs from EBV-transformed cell (12 unique eQTLs, yellow). Both gene RP11-977G19.11 and gene LINC01089 were replicated four times. B Venn diagram illustrating the overlap of pQTLs across different datasets: pQTL discovery cohort (5 pQTLs, green), pQTL replication cohort (8 pQTLs, blue), and inflammation-related pQTL (4 pQTLs, pink). APOF is highlighted as the single pQTL common to all three datasets