Fig. 4
From: Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis
Multi-omics Manhattan plots for mQTL, eQTL, and pQTL associations with psoriasis risk in plasma. A Manhattan plot of mQTL associations. The x-axis represents chromosomal positions, and the y-axis shows the -log10(p) values. Significant mQTLs are highlighted, with key CpG sites labeled (cg00172967, cg26804944, cg02705573, cg00294382, cg24773560). B Manhattan plot of eQTL associations. The plot follows the same format as A. The gene RP11-977G19.11 (ENSG00000257303) is highlighted as a significant eQTL. C Manhattan plot of pQTL associations. The plot maintains the same structure as A and B. The APOF is identified as a significant pQTL