Fig. 3
From: Multi-omics analysis reveals novel causal pathways in psoriasis pathogenesis
Expression quantitative trait loci (eQTLs) associated with psoriasis risk and their replication. A Circular plot depicting eQTLs associated with psoriasis risk in the discovery cohort. The outer ring shows individual gene names. Inner rings represent, from outermost to innermost: p-values (p_HEIDI), SMR statistics (p_SMR_bxy), and odds ratios (OR). B Circular plot showing eQTLs associated with psoriasis risk in the replication cohort. The layout is identical to A. Note the different OR scale compared to A. C Venn diagram-style representation of overlapped eQTL between discovery and replication cohorts. The discovery cohort identified 54 eQTLs, while the replication cohort identified 33 eQTLs. The Venn diagram shows 17 eQTLs that were successfully replicated in both cohorts