Fig. 2

Weighted gene co-expression network analysis to identify differentially expressed time- and immune-related genes (DETIRGs). a Estimation of the scale independence index of the 1–30 soft threshold power (β = 1). b Determination of the mean connectivity of the 1–30 soft threshold power. c Identification and construction of gene co-expression modules that were illustrated as different colors in hierarchical clustering. d Clustering dendrogram of module feature genes. e Correlations between different modules and time points post SCI. Red represented a positive correlation, and green represented a negative correlation. f Venn diagram showing the 13 DETIRGs obtained by intersecting. g Gene ontology (GO) enrichment analysis of DETIRGs in biological processes, cellular components, and molecular functions. h Kyoto encyclopedia of genes and genomes (KEGG) analysis of DETIRGs